The role of a new druggable protein and its interacting partners in blood development and blood diseases
The role of a new druggable protein and its interacting partners in blood development and blood diseases
批准号:
nhmrc : GNT1070687
负责人:
Dr M. Cristina Keightley
金额:
$56.76万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
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英文摘要
Zbtb11 is a druggable protein that is mis-expressed in blood cancers - second biggest cause of cancer death in Australia - and liver cancer, third leading cause of death from cancer worldwide. We have found that it interacts with 2 other proteins with potential roles in these diseases. Our studies examine the nature of these Zbtb11-partner interactions and their particular consequences for blood disorders. Zbtb11 contributions to disease development will be a target for novel disease therapy.
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会议论文
Zbtb11 interactions in haematopoiesis and disease
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批准号:nhmrc : 1070687
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项目类别:Project Grants
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资助金额:$39.18万
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财政年份:2014
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负责人:Dr M. Cristina Keightley
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依托单位:
国内基金
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