Genetic history of human populations

人类遗传史

• 批准号: 293152-2008
• 负责人: Labuda, Damian
• 金额: $ 1.79万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=395825
• 关键词: Genetic; history; human; populations

We present a long-term research program that aims at characterizing the genetic structure of present-day human populations using genetic information from segments of the X-chromosome. Our colleagues following a similar line of work with mtDNA and Y-chromosome have been collecting data for more than two decades in numerous laboratories all over the world. We want to complement this global effort by providing new information from the nuclear genome using X-linked variation. So far this work has provided unusually interesting results, complementing previous findings from other genetic systems such as mtDNA and the Y-chromosome, and most importantly bringing quantitatively new data leading to new hypotheses and views of human population history.

我们提出了一个长期的研究计划，旨在利用X染色体片段的遗传信息来表征当今人类种群的遗传结构。我们的同事从事类似的mtDNA和Y染色体工作，二十多年来一直在世界各地的许多实验室收集数据。我们希望通过使用X连锁变异提供来自核基因组的新信息来补充这一全球努力。到目前为止，这项工作提供了非常有趣的结果，补充了以前从其他遗传系统（如mtDNA和Y染色体）获得的发现，最重要的是带来了定量的新数据，导致了人类人口历史的新假设和观点。