Self-assembled hydrogels as a model for neurodegeneration

自组装水凝胶作为神经退行性变的模型

• 批准号: nhmrc : GNT1106751
• 负责人: Dr Adam Martin
• 金额: $ 59.46万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Boosting Dementia Research Initiative
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/self-assembled-hydrogels-model-neurodegeneration/1346534
• 关键词: Self; assembled; hydrogels; model; neurodegeneration

Alzheimer’s disease (AD) is a neurodegenerative disease which currently affects over 340,000 Australians. Often, symptoms of AD are not apparent until the disease is well advanced, limiting chances of successful treatment. In this project, hydrogels made from biocompatible peptides will be used to grow neural cell culture models to study the development of the disease in its early stages. This will help to develop new diagnostic tools for the early detection of AD.

阿尔茨海默病(AD)是一种神经退行性疾病，目前影响着超过34万澳大利亚人。通常情况下，阿尔茨海默病的症状在疾病进展顺利之前并不明显，这限制了成功治疗的机会。在这个项目中，生物相容多肽制成的水凝胶将被用于培养神经细胞培养模型，以研究疾病早期的发展。这将有助于开发新的诊断工具，以早期发现AD。