Do sex hormones slow biological ageing to improve health outcomes in men?

性激素是否可以减缓生物衰老以改善男性的健康状况？

• 批准号: nhmrc : 1121548
• 负责人: Dr Jennie Hui
• 金额: $ 16.94万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/sex-hormones-slow-outcomes-men/946762
• 关键词: Do; sex; hormones; slow; biological

As the Australian population ages their burden of ill-health increases. Our earlier research showed that higher sex hormone levels are associated with better health outcomes in older men. In this project, we will address the question whether exposure to higher sex hormone levels slows biological ageing in men, reflected in the presence of longer chromosomal ends called telomeres. If so, interventions that raise hormone levels could be tested to preserve health in ageing men.

随着澳大利亚人口的老龄化，他们的健康状况不佳的负担也在增加。我们早期的研究表明，较高的性激素水平与老年男性更好的健康结果有关。在这个项目中，我们将讨论暴露于较高的性激素水平是否会减缓男性的生物衰老，这反映在称为端粒的较长染色体末端的存在上。如果是这样的话，可以测试提高激素水平的干预措施，以保持老年男性的健康。