Slowing the spread of malaria drug resistance by extending the lifespan of the artemisinin derivatives

通过延长青蒿素衍生物的寿命来减缓疟疾耐药性的蔓延

• 批准号: nhmrc : GNT1100394
• 负责人: A/Pr Freya Fowkes
• 金额: $ 39.15万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/slowing-spread-malaria-artemisinin-derivatives/1346117
• 关键词: Slowing; spread; malaria; drug; resistance

Approximately 200 million clinical cases of malaria are treated globally each year. Alarmingly, resistance to the most highly effective antimalarial drugs, has emerged in Southeast Asia, jeopardizing malaria control. This project will develop novel mathematical models that predict the action of the antimalarial drug within an infected individual to inform the malaria community of optimal treatment strategies in areas where resistance has emerged.

全球每年约有 2 亿临床疟疾病例得到治疗。令人震惊的是，东南亚出现了对最有效的抗疟药物的耐药性，危及疟疾的控制。该项目将开发新颖的数学模型，预测抗疟药物在感染者体内的作用，以便为疟疾界提供在出现耐药性的地区的最佳治疗策略。