Studies on new mononuclear and polynuclear platinum compounds with trans-geometry

新型单核和多核反几何铂化合物的研究

• 批准号: nhmrc : 571235
• 负责人: Dr Fehmida Fasim
• 金额: $ 4.58万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Postgraduate Scholarships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/studies-new-mononuclear-trans-geometry/116182
• 关键词: Studies; new; mononuclear; polynuclear; platinum

Even in post-genomic age cisplatin continues to be widely used as a highly successful anticancer drug. However, the drug has a number of side effects and does not show activity against many types of cancer. in some cases, resistant form of cancer develops for which the drug does not function. An example is ovarian cancer. This project aims to arrive at new platinum-based anticancer drugs targeted to ovarian cancer.

即使在后基因组时代，顺铂仍然作为一种非常成功的抗癌药物被广泛使用。然而，这种药物有许多副作用，对许多类型的癌症没有显示出活性。在某些情况下，癌症的耐药形式发展，药物对其不起作用。一个例子是卵巢癌。该项目旨在开发针对卵巢癌的新型铂类抗癌药物。