TGFB1 is a pivitol regulator of endometriotic lesion development
TGFB1 is a pivitol regulator of endometriotic lesion development
批准号:
nhmrc : 1012950
负责人:
A/Pr Mary (Louise) Hull
金额:
$29.26万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
Endometriosis occurs when the tissue that lines the womb is found in the pelvic cavity. 10% of reproductive aged women have endometriosis and suffer from debilitating pelvic pain and subfertility. We have shown that transforming growth factor (TGFB1) is central to the growth of endometriosis and that its absence suppresses disease development. We hope to clarify the role of TGFB1 in endometriosis, in order to develop better therapeutic options for women incapacitated by this disease.
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