Trajectories of circulating testosterone and estradiol and implications for the health of ageing men.

睾丸激素水平低的老年男性更不健康。然而，尚不清楚年龄是否会导致睾丸激素水平下降，从而易患疾病，还是激素水平的变化是由先前存在的疾病引起的。我们之前在2001-04年测量了西澳大利亚州老年男性的性激素水平。通过测量2011- 2012年从1400名男性中采集的新样本中的激素水平，我们将阐明性激素水平的轨迹及其与健康老龄化的关系。

Older men with low testosterone levels have more ill-health. However, it is unclear whether age causes testosterone levels to fall, predisposing to disease, or whether changes in hormone levels result from pre-existing illness. We previously measured sex hormone levels in older men in Western Australia in 2001-04. By measuring hormone levels in new samples from 1400 of these men taken in 2011-12, we will clarify trajectories of sex hormone levels and their relationship to healthy ageing.