Trajectories of circulating testosterone and estradiol and implications for the health of ageing men.

睾丸激素水平低的老年男性健康状况更差。然而，目前还不清楚年龄是否会导致睾丸激素水平下降，易患疾病，或者激素水平的变化是否是由于预先存在的疾病。我们之前在2001-04年测量了西澳大利亚州老年男性的性激素水平。通过测量2011年至2012年从1400名男性中提取的新样本中的激素水平，我们将阐明性激素水平的轨迹及其与健康老龄化的关系。

Older men with low testosterone levels have more ill-health. However, it is unclear whether age causes testosterone levels to fall, predisposing to disease, or whether changes in hormone levels result from pre-existing illness. We previously measured sex hormone levels in older men in Western Australia in 2001-04. By measuring hormone levels in new samples from 1400 of these men taken in 2011-12, we will clarify trajectories of sex hormone levels and their relationship to healthy ageing.