Traumatic Brain Injury, Post Traumatic Stress Disorder and the Risk of Neurodegenerative Disease: a study of tau and beta-amyloid accumulation, brain structure and function several decades after injury.

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The study aims to better understand the association between traumatic brain injury (TBI), post traumatic stress disorder (PTSD) and dementia, specifically Alzheimer’s disease (AD) and chronic traumatic encephalopathy (CTE). The study will examine retired AFL players, road trauma victims and Vietnam veterans with advanced imaging using PET brain scans for the abnormal brain deposits typical of AD and CTE and assess the risk of later developing these diseases from head injury and PTSD.