Trichomonas vaginalis: prevalence in an urban indigenous population and validation of new assays

阴道毛滴虫：城市土著人群中的患病率和新检测方法的验证

• 批准号: nhmrc : 216706
• 负责人: A/Pr Kathryn Panaretto
• 金额: $ 5.93万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/trichomonas-vaginalis-prevalence-new-assays/95561
• 关键词: Trichomonas; vaginalis; prevalence; urban; indigenous

The infection called trichomonas is the commonest sexually transmitted infection (STI) world-wide. It is caused by a parasite and is particularly common amongst disadvantaged, poor communities. It is important to diagnose and treat (readily available treatments exist) this infection because it is linked with early birth in pregnant women and increases the spread of HIV-AIDS virus. The diagnosis has not changed for decades until recently, when a new more sensitive test became available.Wehave adapted it to work on self-collected specimens such as in-out tampons or urines. Proof that this new diagnostic tool is better, is needed in Australia in high-risk groups such as Aboriginal and Torres Strait Islander communities where other STIs have already been shown to be at high rates. How this parasite causes disease in humans is poorly studied. We plan to test this new diagnostic method and compare it to traditional tests in a high-risk population and to ultimately study how the parasite causes disease.

毛滴虫感染是全世界最常见的性传播感染 (STI)。它是由寄生虫引起的，在弱势、贫困社区中尤其常见。诊断和治疗这种感染（已有现成的治疗方法）非常重要，因为它与孕妇早产有关，并会增加艾滋病病毒的传播。这种诊断几十年来一直没有改变，直到最近出现了一种新的更灵敏的测试。我们对其进行了调整，使其适用于自行收集的样本，例如进出卫生棉条或尿液。澳大利亚的高风险群体需要证明这种新的诊断工具更好，例如原住民和托雷斯海峡岛民社区，这些地区的其他性传播感染的发病率已经很高。这种寄生虫如何引起人类疾病的研究很少。我们计划测试这种新的诊断方法，并将其与高危人群中的传统测试进行比较，最终研究寄生虫如何引起疾病。