Type 2 diabetic renal complications and microvascular injury: novel predictors of onset and progression, mechanisms of association with cardiovascular disease and the benefits of fenofibrate.

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We will investigate the mechanisms of diabetic complications related to kidney and blood vessel disease, focusing on identifying people at greater risk and ways to improve or prevent these complications. In addition, we will look at how diabetic kidney disease affects non-kidney related problems like heart disease and examine the benefit of fenofibrate on both. This greater understanding will aid further drug development in kidney and cardiovascular diseases.