Understanding the mechanisms that regulate spleen organogenesis
Understanding the mechanisms that regulate spleen organogenesis
批准号:
nhmrc : 1078247
负责人:
Jonathan Tan
金额:
$27.62万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
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英文摘要
Spleen is a organ with regenerative capacity but the cells driving this have been largely unexplored. A cell-type essential for spleen tissue formation was recently discovered, termed a spleen organiser cell. We are now are attempting to understand where these cells originate from, what cells they develop into, and which genes are important for spleen regeneration. These findings will advance fundamental knowledge of spleen development and lead to better strategies for spleen transplant therapy.
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