Understanding the myometrial transition at term and preterm labour to guide tocolysis
Understanding the myometrial transition at term and preterm labour to guide tocolysis
了解足月和早产时子宫肌层的转变以指导安胎
批准号：
nhmrc : GNT1126795
负责人：
Dr Sonika Tyagi
金额：
$80.84万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2017
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2017-01-01 至 --
中文摘要
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英文摘要
This grant seeks to understand how the muscle cells of the uterus transform at the time of labour. We propose that this transformation is organised by enzymes that modify the histones around key genes. We will test if a similar pathway operates in cases of preterm labour. The results will guide the development of new ways of treating premature labour that will use targeted nanoparticles to deliver siRNA directly to the muscle cells of the uterus.
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