Understanding the role of three-dimensional genome organisation in B cell lineage commitment and leukaemia.
Understanding the role of three-dimensional genome organisation in B cell lineage commitment and leukaemia.
批准号:
nhmrc : 1124081
负责人:
Dr Timothy Johanson
金额:
$21.75万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31
中文摘要
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英文摘要
Every one of your nuclei contain 2 metres of DNA. This DNA is 300,000 times longer than the nucleus itself. In order to fit into this space, while maintaining access to crucial genes, the DNA forms a fantastically ordered three-dimensional structure. This intricate organisation is crucial to health, with even minute changes driving diseases, such as cancer and heart disease. We propose using new technology to understand how this organisation changes during immune cell development and leukaemia.
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Understanding the role of three-dimensional genome organisation in B cell lineage commitment and leukaemia.
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批准号:nhmrc : GNT1124081
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项目类别:Early Career Fellowships
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资助金额:$31.88万
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财政年份:2017
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负责人:Dr Timothy Johanson
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依托单位:
国内基金
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项目类别:面上项目
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