Unravelling the behavioural and brain mechanisms of compulsive disorders, and new ways to treat them

强迫障碍，如强迫症和物质使用障碍，是慢性的，使人衰弱的，对个人和社会都是巨大的代价。这些疾病加在一起影响了10%以上的人口。此外，其中40-60%的人对目前的治疗有抗药性。目前的项目旨在提高临床前研究的基础上，我们了解这些疾病的行为和大脑机制，以及如何治疗它们。

Disorders of compulsion, such as obsessive-compulsive disorder and substance use disorder, are chronic, debilitating, and present a significant cost to the individual and to society. Together, these disorders affect more than 10% of the population. Moreover, 40-60% of these individuals are resistant to current treatment. The current project is aimed at improving the preclinical research underlying our understanding the behavioural and brain mechanisms of such disorders and how to treat them.