Export of effector proteins by P. falciparum to the infected red blood cell

恶性疟原虫将效应蛋白输出到受感染的红细胞

• 批准号: DE120102263
• 负责人: Dr Neta Regev-rudzki
• 金额: --
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-02 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE120102263
• 关键词: Export; effector; proteins; P.; falciparum

Infection by the malaria parasite has lethal consequences for humans. The parasite exports hundreds of proteins via a translocon to commandeer the red blood cell. This project aims to determine the function of one of the major translocon components and determine if it is a viable target for anti-malarial drug development.

疟疾寄生虫感染对人类具有致命后果。这种寄生虫通过转座子输出数百种蛋白质来霸占红细胞。该项目旨在确定一个主要转座子成分的功能，并确定它是否是抗疟疾药物开发的可行靶点。