Use of molecular resistance assays to provide alterative oral treatment strategies for gonorrhoea in Indigenous and other high-risk populations; a randomised cluster trial

使用分子耐药性测定为土著和其他高危人群的淋病提供替代性口服治疗策略；

• 批准号: nhmrc : GNT1122141
• 负责人: A/Pr David Whiley
• 金额: $ 82.87万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/use-molecular-resistance-cluster-trial/1347250
• 关键词: Use; molecular; resistance; assays; provide

Gonorrhoea has now developed resistance to almost all antibiotics that have been used to treat it. In this study, we will investigate a new treatment approach that selects antibiotics on a patient-by-patient basis. We will use new molecular assays to first test if a gonorrhoea strain infecting a patient is susceptible to an antibiotic, and will then treat on the basis of this result. By doing so, we will optimize our use of antibiotics and improve treatment strategies for gonorrhea.

淋病现在已经对几乎所有用于治疗它的抗生素产生了耐药性。在这项研究中，我们将研究一种新的治疗方法，根据患者的情况选择抗生素。我们将使用新的分子检测方法，首先检测感染患者的淋病菌株是否对抗生素敏感，然后根据这一结果进行治疗。通过这样做，我们将优化抗生素的使用，改善淋病的治疗策略。