Novel role for the universal signalling molecule nitric oxide within biofilm communities and across a biofilm-host interface

通用信号分子一氧化氮在生物膜群落和生物膜-宿主界面中的新作用

• 批准号: DE120101604
• 负责人: Dr Nicolas Barraud
• 金额: $ 26.91万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-02 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE120101604
• 关键词: Novel; role; universal; signalling; molecule

Biofilms on wet surfaces and tissues cause major problems by resisting antimicrobials. This project aims at exploiting how natural host response control systems alleviate biofilm build up and can be used to control biofilms in a non-toxic fashion. Countless environmental and clinical applications will benefit from reduced usage of antibiotics.

潮湿表面和组织上的生物膜通过抵抗抗菌剂而引起主要问题。该项目旨在利用自然宿主反应控制系统如何减轻生物膜的建立，并可用于以无毒的方式控制生物膜。无数的环境和临床应用将受益于减少抗生素的使用。