Venesection or expectant management for moderate iron overload in HFE related hereditary haemochromatosis

静脉切开术或期待疗法治疗 HFE 相关遗传性血色素沉着病中度铁超负荷

• 批准号: nhmrc : 1026394
• 负责人: A/Pr Amanda Nicoll
• 金额: $ 56.89万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/venesection-expectant-management-hereditary-haemochromatosis/110492
• 关键词: Venesection; expectant; management; moderate; iron

Haemochromatosis is a preventable genetic iron overload disorder. Untreated, it can shorten life due mainly to liver cirrhosis and cancer. It can be prevented by blood donation to maintain normal iron levels. It is unclear, however, whether treatment is necessary when individuals have moderate elevation of iron in the body. This research project will study the effects of treatment in this group by assessing a number of scans, questionnaires and blood tests in treated and untreated individuals.

血色素沉着病是一种可预防的遗传性铁超载疾病。如果不治疗，它会缩短寿命，主要是由于肝硬化和癌症。它可以通过献血来预防，以维持正常的铁水平。然而，目前尚不清楚当个体体内铁含量适度升高时是否有必要进行治疗。该研究项目将通过对接受治疗和未接受治疗的个体进行一系列扫描、问卷调查和血液测试来研究治疗对这一群体的影响。