New chemometric tools for chemistry and systems biology

用于化学和系统生物学的新化学计量学工具

• 批准号: 46316-2008
• 负责人: Wentzell, Peter
• 金额: $ 3.13万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=451058
• 关键词: New; chemometric; tools; chemistry; systems

The advance of analytical instrumentation has led to the availability of unprecedented amounts of data for individual samples, and this phenomenon has spilled over into the realm of biology, where high throughput analytical approaches such as microarrays, protein mass spectrometry, and high field NMR spectroscopy have revolutionized research into cell biology. These advances have been essential to address the increasing complexity of the analytical samples and the questions posed by scientists from diverse fields of study. Nowhere is this more true than in the nascent field of systems biology, which promises not only a broader understanding of biological processes, but concomitant advances in areas such as drug discovery and personalized medicine.

分析仪器的进步使单个样品的数据量达到了前所未有的水平，这一现象已经蔓延到生物学领域，在这些领域，高通量分析方法，如微阵列、蛋白质质谱学和高场核磁共振谱，已经彻底改变了细胞生物学的研究。这些进展对于解决分析样本日益复杂的问题和来自不同研究领域的科学家提出的问题至关重要。这一点在新生的系统生物学领域表现得尤为明显，它不仅承诺对生物过程有更广泛的理解，而且在药物发现和个性化医学等领域也会随之取得进展。