Elucidation of endopolygalacturonase structural determinants
Elucidation of endopolygalacturonase structural determinants
批准号:
138654-2008
负责人:
Beauregard, Marc
金额:
$1.75万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-01-01 至 2011-12-31
中文摘要
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英文摘要
Enzymes are becoming increasingly important products for several industries. They are safe for the environment, cheaper than ever, and, when used under optimal conditions, much more efficient than chemical catalysts. With recent advances in protein engineering and directed evolution, customized enzymes will become available for industrial processes for which the native enzymes were unsuitable. At the heart of enzyme efficacy as industrial biocatalysts are stability issues. Indeed, enzymes have to stand rather harsh conditions in order to provide economical alternatives to polluting chemicals; customizing enzymes for industrial application will therefore require an in-depth understanding of stability determinants in proteins.
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