Interfacial forces studied using scanning probe methods

使用扫描探针方法研究界面力

• 批准号: 194109-2009
• 负责人: Horton, Hugh
• 金额: $ 3.64万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=452610
• 关键词: Interfacial; forces; studied; using; scanning

Why is tape sticky? Why do we slip on ice? These are some everyday questions that can be answered by considering the fundamental nature of surface or interfacial interactions. To try and address these questions, we need to consider the nature of the chemical forces at the junction between two interfaces. Can we quantify them? And can we modify the chemistry of a surface so that it will bind only to some molecules but not to others? The questions noted above are fundamental ones, but there are also a number of practical problems which can be addressed by answering these questions. For example, how we can separate or purify mixtures of several molecules leading, for example, to the development of better drugs. What are the forces that control the adsorption of enzymes or proteins on the surface of a detection device. Answering this will allow development of analytical devices for quick screening for cancer or other diseases. Another application is the adsorption of trace contaminants to soils, leading to better environmental remediation techniques.

为什么胶带粘粘的？ 为什么我们会在冰上滑倒？ 这些是一些日常问题，可以通过考虑表面或界面相互作用的基本性质来回答。为了尝试解决这些问题，我们需要考虑两个界面交界处的化学力的性质。 我们能量化它们吗？ 我们能否改变表面的化学性质，使其只与某些分子结合，而不与其他分子结合？上述问题是基本问题，但也有一些实际问题可以通过回答这些问题来解决。 例如，我们如何分离或纯化几种分子的混合物，从而开发出更好的药物。 控制酶或蛋白质吸附在检测设备表面的力是什么？ 这将允许开发用于快速筛查癌症或其他疾病的分析设备。另一个应用是将痕量污染物吸附到土壤中，从而产生更好的环境补救技术。