A worldwide study of cancer risk for Lynch syndrome

林奇综合征癌症风险的全球研究

• 批准号: nhmrc : 1063840
• 负责人: Dr Aung Win
• 金额: $ 47.39万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/worldwide-study-cancer-lynch-syndrome/454595
• 关键词: worldwide; study; cancer; risk; Lynch

People with the genetic Lynch syndrome are more likely to get cancer but we cannot accurately predict who will get cancer and when. Doctors need this information to improve cancer prevention. Large collaborative studies are needed for this research. We have agreement from the 115 researchers to combine, into a single resource, 8,863 family trees of Lynch syndrome. We will analyse this data to determine the risk of cancer and whether it differs by sex, age, or nationality.

患有遗传性林奇综合症的人更有可能患上癌症，但我们无法准确预测谁会患上癌症以及何时患上癌症。医生需要这些信息来改善癌症预防。这项研究需要大规模的合作研究。我们已获得 115 名研究人员的同意，将 8,863 个林奇综合征家谱合并为一个资源。我们将分析这些数据，以确定患癌症的风险以及它是否因性别、年龄或国籍而异。