Pioneering alpine epigenomics to discover adaptive genetic elements

对于促进适应气候变化的DNA元素，本土植物的遗传密码还有待探索。由于表观基因组学的最新进展，这些元素现在被发现的时机已经成熟，可以快速鉴定。这项提议旨在发现生活在澳大利亚脆弱的高地的蜡质风铃草中与高温相关的元素。预期的结果包括对本土植物基因调控机制的新见解；产生用于遗传保护的资源，以及促进对澳大利亚植物区系的进一步分子研究。这将通过揭示本土植物的基因组调控，从而提高预测气候变化影响的能力，从而提供显著的好处。

The genetic code of native plants are yet to be explored for DNA elements that promote resilience to climate change. These elements are now ripe for discovery due to recent advances in epigenomics allowing for rapid identification. This proposal aims to discover heat-associated elements in waxy bluebells, which inhabit Australia’s vulnerable high country. Expected outcomes include new insights on gene regulatory mechanisms in native plants; the generation of resources for genetic conservation, and catalysing further molecular research into Australian flora. This should provide significant benefits by revealing genome regulation in native plants, thereby improving the ability to predict the impacts of climate change.