Novel mechanisms of bacterial arsenic metabolism - arsenate reduction and arsenite oxidation

细菌砷代谢的新机制——砷酸盐还原和亚砷酸盐氧化

• 批准号: ARC : DP0209802
• 金额: $ 21.7万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2004-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-mechanisms-bacterial-arsenite-oxidation/75798
• 关键词: Novel; mechanisms; bacterial; arsenic; metabolism

Novel mechanisms of bacterial arsenic metabolism - arsenate reduction and arsenite oxidation. Novel arsenic metabolising bacteria (i.e., arsenate respiring and arsenite oxidising), which are both phylogenetically and physiologically unique, have been isolated from arsenic-contaminated areas in Australia. The arsenate respiring bacterium, Chrysiogenes arsenatis, is of particular interest as it is the only organism reported able to respire with arsenate using the respiratory substrate acetate as the electron donor. It is proposed that physiological, biochemical and molecular biological studies be carried out to better understand the mechanisms by which these organisms metabolise arsenic. The knowledge gained from these studies will have worldwide application in the development of an arsenic bioremediation system.

细菌砷代谢的新机制--砷还原和亚砷酸盐氧化。从澳大利亚砷污染地区分离到了新的砷代谢细菌(即砷酸盐呼吸和亚砷酸盐氧化)，它们在系统发育和生理上都是独一无二的。砷酸盐呼吸细菌是一种特别令人感兴趣的细菌，因为据报道，它是唯一一种能够利用呼吸底物乙酸盐作为电子供体与砷酸盐呼吸的生物。建议开展生理、生化和分子生物学研究，以更好地了解这些生物代谢砷的机制。从这些研究中获得的知识将在世界范围内应用于开发砷生物修复系统。