The plasma catecholamine surge at birth: its role in determining variations in brain function.

出生时血浆儿茶酚胺激增：其在决定大脑功能变化中的作用。

• 批准号: 138196-2010
• 负责人: Boksa, Patricia
• 金额: $ 2.55万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=475794
• 关键词: plasma; catecholamine; surge; birth; its

Birth is a unique process. Our long term goal is to better understand the physiology of birth - in particular, to understand how regulatory mechanisms protect the brain during birth. During a normal birth, the newborn experiences a decrease in oxygen (hypoxia) with each contraction of the mother's uterus. In addition there is a fall in the newborn's blood oxygen during 2nd stage labor compared to 1st. However little is known about mechanisms that might protect the newborn brain from hypoxia during normal birth or during more severe hypoxia such as in a very long labor.

出生是一个独特的过程。 我们的长期目标是更好地了解出生的生理学-特别是了解在出生期间调节机制如何保护大脑。 在正常分娩期间，新生儿随着母亲子宫的每次收缩而经历氧气减少（缺氧）。 此外，与第一阶段相比，第二阶段分娩期间新生儿的血氧含量下降。 然而，很少有人知道的机制，可能会保护新生儿大脑缺氧在正常生产或在更严重的缺氧，如在一个非常长的劳动。