The Chemistry and Biochemistry of Chromium: Cancer and Nutrition

铬的化学和生物化学：癌症和营养

• 批准号: ARC : DP0208409
• 金额: $ 98.23万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/the-chemistry-biochemistry-cancer-nutrition/62173
• 关键词: Chemistry; Biochemistry; Chromium; Cancer; Nutrition

The Chemistry and Biochemistry of Chromium: Cancer and Nutrition. Of all of the human carcinogens, chromium(VI) has the highest level of occupational exposure, and is of increasing concern as an environmental carcinogen, as highlighted by the film Erin Brockovitch. Similarly, chromium(III) nutritional supplement consumption by humans and animals is rising rapidly, despite mounting concerns about their cancer risks. However, the complexity of Cr biochemistry is such that it is still poorly understood. This project aims at providing new insights into Cr biochemistry that are of relevance in evaluating risk factors for occupational and environmental exposure and for producing safer Cr dietary supplements.

铬的化学和生物化学：癌症和营养。在所有人类致癌物中，六价铬的职业接触水平最高，并且作为一种环境致癌物越来越受到关注，正如电影艾琳·布罗科维奇 (Erin Brockovitch) 所强调的那样。同样，尽管人们越来越担心三价铬营养补充剂的癌症风险，但人类和动物对三价铬营养补充剂的消费量正在迅速增加。然而，铬生物化学的复杂性使得人们对它仍然知之甚少。该项目旨在提供对铬生物化学的新见解，这对于评估职业和环境暴露的风险因素以及生产更安全的铬膳食补充剂具有相关性。