Structural and functional adaptation of supraoptic neurons to sustained hyperosmolality

视上神经元对持续高渗透压的结构和功能适应

• 批准号: 177541
• 负责人: Fisher Thomas E
• 金额: $ 6.34万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2010-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=177541&lang=en
• 关键词: Ca+ Currents; Channel Translocation; Osmosensitivity; Patch Clamp; Supraoptic Nucleus; Vasopressin

Proper cardiovascular function in mammals depends on keeping the concentration of salts in the blood at a constant level. A critical part of this regulation are neurons in the brain that sense changes in saltiness (or osmolality) and release a hormone (va

哺乳动物正常的心血管功能取决于保持血液中盐的浓度在一个恒定的水平。这种调节的一个关键部分是大脑中的神经元，它们感知盐度（或渗透压）的变化并释放一种激素（va