Biology of circoviruses

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Circoviruses are small, non-enveloped icosahedral viruses that are emerging as important pathogens of several animal species. Porcine circovirus type 2 (PCV-2) was first discovered in Canada in 1991 as the infectious agent for post-weaning multisystemic wasting syndrome (PMWS), a progressive disease that occurs in piglets. Since its original discovery, PCV-2 has been identified world-wide as an important pathogen causing significant economic losses in swine herds. Similarly, the etiological agent of infectious chicken anemia, chicken anemia virus (CAV) has also been shown to be a circovirus and controlling outbreaks of this virus