课题基金 / 基金详情

Regulation, downstream targets and functional specificity of the MAP kinases ERK1 and ERK2

Regulation, downstream targets and functional specificity of the MAP kinases ERK1 and ERK2
MAP 激酶 ERK1 和 ERK2 的调节、下游靶标和功能特异性
批准号：
238152
负责人：
Meloche Sylvain
金额：
$65.88万
依托单位：
Institute for Research in Immunology and Cancer (Montreal, QC)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-09-01 至 2016-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=238152&lang=en
关键词：
Animal Models Of Disease Cell Differentiation Cell Proliferation Embryonic Development Map Kinases Mouse Models Phosphoproteomics Phosphorylation Regulation Signal Transduction

项目摘要

项目成果

Meloche Sylvain的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The MAP kinases ERK1 and ERK2 are a family of enzymes that play important roles in the control of cell proliferation and differentiation. Accumulating evidence suggests that the ERK1/ERK2 signaling pathway is implicated in the pathogenesis of human diseas
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Role and therapeutic potential of the atypical MAP kinase ERK3 in basal-like breast cancer progression
Development and preclinical validation of first-in-class dual inhibitors of the atypical MAP kinases ERK3 and ERK4
Role and therapeutic potential of ERK3/ERK4 MAP kinases in acute kidney injury
Targeting the degradation of the cyclin-dependent kinase inhibitor p21 as a novel approach to cancer therapy
海外基金