Gipr and the control of glucose homeostasis

Gipr 和葡萄糖稳态的控制

• 批准号: 237326
• 负责人: Drucker Daniel J
• 金额: $ 56.98万
• 依托单位: Lunenfeld-Tanenbaum Research Institute (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2016-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=237326&lang=en
• 关键词: Diabetes; Intestine; Obesity; Peptide Hormones

Incretin hormones are secreted from the gut and aid in the disposal of ingested nutrients by augmenting insulin secretion following meal ingestion. The two pricipal incretin hormones, GLP-1 and GIP, potentiate glucose-dependent insulin secretion by activa

肠促胰岛素激素从肠道分泌，并通过增加膳食摄入后的胰岛素分泌来帮助处理摄入的营养素。两种主要的肠促胰岛素激素GLP-1和GIP通过激活胰岛素受体增强葡萄糖依赖性胰岛素分泌。