Role of lipid mediators in controlling migration and chemo-resistance in breast cancer cells

脂质介质在控制乳腺癌细胞迁移和化疗耐药中的作用

• 批准号: 248570
• 负责人: Brindley David N
• 金额: --
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=248570&lang=en
• 关键词: Autotaxin; Chemo-Resistance; Doxorubicin; Lysophosphatidate; Phospholipase D; Sphingosine 1-Phosphate; Sphingosine Kinase; Taxol

Treatment of breast and other cancers by a combination of surgery and chemotherapy is often unsuccessful and patients die. This is explained in two ways. Some tumor cells survive the surgery or they may have already spread to other areas of the body. S

通过手术和化疗相结合来治疗乳腺癌和其他癌症通常是不成功的，病人会死亡。这有两种解释。一些肿瘤细胞在手术中存活下来，或者它们可能已经扩散到身体的其他部位。年代