Genetics and Epigenetics of Serotonin System in Suicidal Behaviour: CpG SNP Mapping, Methylation and Allelic Imbalance Analysis

自杀行为中血清素系统的遗传学和表观遗传学：CpG SNP 定位、甲基化和等位基因不平衡分析

• 批准号: 240155
• 负责人: De Luca Vincenzo
• 金额: $ 44.85万
• 依托单位: Centre for Addiction and Mental Health (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2016-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=240155&lang=en
• 关键词: Epigenetics; Genetics; Methylation; Suicide

Schizophrenia and bipolar disorder affect hundreds of thousands of Canadians and their families. Both disorders are associated with a high risk of suicide. Several studies provide evidence that genetic factors influence suicidal behavior. The major aim of

精神分裂症和躁郁症影响着成千上万的加拿大人和他们的家庭。这两种疾病都与自杀的高风险有关。一些研究提供了遗传因素影响自杀行为的证据。的主要目的