Role of nuclear metabotropic glutamate receptors in persistent nociception

核代谢型谷氨酸受体在持续性伤害感受中的作用

• 批准号: 237392
• 负责人: Coderre Terence J
• 金额: $ 55.34万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2016-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=237392&lang=en
• 关键词: Behavioural Testing; Calcium Signaling; Glia; Glutamate; Glutamate Binding; Glutamate Transporters; Mglurs; Nuclear Receptors; Pain; Subcellular Membrane Fractionation

Neurotransmitter receptors are normally found on the outer cell membrane of nerve cells or neurons. Some receptors have been found as well inside neurons on the membrane of the cell's nucleus. We propose to examine whether increases in newly discovered nu

神经递质受体通常位于神经细胞或神经元的外细胞膜上。在细胞核膜上的神经元内也发现了一些受体。我们建议研究新发现的nu是否增加