Understanding the mechanisms by which resveratrol prevents doxorubicin-induced cardiac dysfunction and heart failure

了解白藜芦醇预防阿霉素引起的心功能障碍和心力衰竭的机制

• 批准号: 237468
• 负责人: Dyck Jason R
• 金额: $ 51.23万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2016-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=237468&lang=en
• 关键词: Cardiac Metabolism; Chemotherapy; Doxorubicin; Heart Failure

While patients who have undergone chemotherapy may be cured of cancer, many suffer from drug-induced damage to other organs, including the heart and blood vessels. Of concern is the fact that patients who show immediate heart injury must be taken off of t

虽然接受化疗的患者可能治愈癌症，但许多人患有药物引起的其他器官损伤，包括心脏和血管。令人关注的是，显示出立即心脏损伤的患者必须停止治疗。