Title: Intervertebral Disc Degeneration and Pain

标题： 椎间盘退变和疼痛

• 批准号: 238808
• 负责人: Haglund Lisbet A
• 金额: $ 23.75万
• 依托单位: McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=238808&lang=en
• 关键词: Age-Related Degeneration; Bioreactor Organ Culture; Human Intervertebral Disc; Isolated Sensory Neuron Culture; Micro-Mechanical Force; Molecular Genetic Analyses; Nerve Growth Factor; Nerve Ingrowth

Introduction: At present little is known about the molecular mechanisms involved in pain generation associated with intervertebral discs degeneration. At least two different mechanisms or a combination of the two could potentially lead to tissue breakdow

简介：目前对椎间盘退变疼痛产生的分子机制知之甚少。至少有两种不同的机制或两者的结合可能导致组织破裂。