Discovery of a Novel Anti-fibrogenic factor and its Therapeutic evaluation

新型抗纤维化因子的发现及其治疗评价

• 批准号: 240703
• 负责人: Ghahary Aziz
• 金额: $ 11万
• 依托单位: Vancouver Coastal Health Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=240703&lang=en
• 关键词: Burn; Fibrosis; Hypertrophic Scarring; Wound Healing

Fibrosis seen in different organs such as skin, liver, lung, kidney and arteries is a serious pathologic disorder in which the properties of normal tissue are disturbed due to an alteration in the extracellular matrix (ECM) composition and organization.

在不同器官如皮肤、肝、肺、肾和动脉中观察到的纤维化是一种严重的病理性疾病，其中正常组织的性质由于细胞外基质（ECM）组成和组织的改变而受到干扰。