Role of PTEN nuclear translocation in NMDAR-mediated exciotoxic neuronal death in Huntington's Disease
Role of PTEN nuclear translocation in NMDAR-mediated exciotoxic neuronal death in Huntington's Disease
批准号:
245821
负责人:
Girling Kimberly D
金额:
$0.0万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-10-01 至 2014-10-01
中文摘要
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英文摘要
The NMDA receptor (NMDAR) is a key receptor in the brain for excitatory neurotransmission. Over-excitation of NMDARs leads to excitotoxicity, which has shown to have a role in the pathogenesis of several neurological diseases such as stroke, ALS and Hunt
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Characterizing and validating SREBP1 inhibition as a novel neuroprotective therapeutic for treating NMDAR-mediated excitotoxic neuronal damage
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批准号:182423
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项目类别:Studentship Programs
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资助金额:$1.27万
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财政年份:2009
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负责人:Girling Kimberly D
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依托单位:
海外基金