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Role of PTEN nuclear translocation in NMDAR-mediated exciotoxic neuronal death in Huntington's Disease

Role of PTEN nuclear translocation in NMDAR-mediated exciotoxic neuronal death in Huntington's Disease
PTEN 核易位在亨廷顿病 NMDAR 介导的兴奋性神经元死亡中的作用
批准号:
245821
负责人:
Girling Kimberly D
金额:
$0.0万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-10-01 至 2014-10-01

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中文摘要
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英文摘要
The NMDA receptor (NMDAR) is a key receptor in the brain for excitatory neurotransmission. Over-excitation of NMDARs leads to excitotoxicity, which has shown to have a role in the pathogenesis of several neurological diseases such as stroke, ALS and Hunt
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Characterizing and validating SREBP1 inhibition as a novel neuroprotective therapeutic for treating NMDAR-mediated excitotoxic neuronal damage
  • 批准号:
    182423
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2009
  • 负责人:
    Girling Kimberly D
  • 依托单位:
海外基金