The physiological impact of postmenopausal oophorectomy on hormone levels in women with BRCA1 mutation

绝经后卵巢切除术对 BRCA1 突变女性激素水平的生理影响

• 批准号: 251461
• 负责人: Narod Steven A
• 金额: $ 30.07万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-10-01 至 2014-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=251461&lang=en
• 关键词: Androgens; Aromatase; Brca1/Brca2; Breast Biopsy; Breast Cancer; Diagnostics; Estrogens; Microfluidics; Oophorectomy; Postmenopausal

"Hormonal factors are critical in determining a woman's risk of developing breast cancer. This is true both for women in the general population and for women with an inherited BRCA1 or BRCA2 mutation. Much of the evidence for hormonal breast carcinogenesi

“荷尔蒙因素是决定女性患乳腺癌风险的关键因素。对于普通人群和携带BRCA1或BRCA2基因突变的女性来说都是如此。荷尔蒙导致乳腺癌的证据很多。