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Effects of phosphorylation on the structure and interactions of the sulfonylurea receptor's nucleotide binding domains

Effects of phosphorylation on the structure and interactions of the sulfonylurea receptor's nucleotide binding domains
磷酸化对磺酰脲受体核苷酸结合域结构和相互作用的影响
批准号：
257420
负责人：
de Araujo Elvin D
金额：
$7.65万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-10-01 至 2014-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=257420&lang=en
关键词：
Abc Transporters Fluoresence Spectroscopy Katp Channels Nmr Spectroscopy Nucleotide Binding Domais Phosphorylation Protein Dynamics Protein Structure Protein-Protein Interactions Sulfonylurea Receptors

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英文摘要
Healthy hearts require specific levels of potassium to function properly. The amount of potassium that enters heart cells is controlled by a protein, SUR2A. Problems with this protein are responsible for a number of cardiovascular disorders, such as heart
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