Structural and functional characterization of Pseudomonas aeruginosa minor pilins

铜绿假单胞菌小菌毛蛋白的结构和功能表征

• 批准号: 258472
• 负责人: Nguyen Ylan
• 金额: $ 7.65万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-10-01 至 2014-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=258472&lang=en
• 关键词: Functional Diversity; Minor Pilins; Pilus Assembly; Protein Purification; Protein-Protein Interactions; Pseudomonas Aeruginosa; Structure; Therapeutic Targets; Type Iv Pili; X-Ray Crystallography

Pseudomonas aeruginosa is among the most common causes of hospital-acquired infections. This bacterium can take advantage of a weakened immune system and cause infections in people with severe burns, HIV and cancer. It is also a cause of chronic lung infe

铜绿假单胞菌是医院获得性感染的最常见原因之一。这种细菌可以利用免疫系统减弱的优势，导致严重烧伤、艾滋病毒和癌症患者感染。这也是慢性肺感染的一个原因