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Macromolecular crowding in protein misfolding and aggregation studied by single-molecule force spectroscopy

Macromolecular crowding in protein misfolding and aggregation studied by single-molecule force spectroscopy
单分子力谱研究蛋白质错误折叠和聚集中的大分子拥挤
批准号：
242784
负责人：
Hoffmann Armin
金额：
$6.56万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-10-01 至 2013-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=242784&lang=en
关键词：
Macromolecular Crowding Parkinsin'S Disease Prion Disease Protein (Mis-)Folding Diseases Protein Aggregation Single-Molecule Force Spectroscopy

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英文摘要
In order to fulfill their essential roles in the cell, proteins have to fold into specific three-dimensional structures. Understanding how this takes place is a key scientific challenge, especially because proteins can also fold into the wrong structures
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