MODERN BIOBUBBLE UNITS TO SUPPORT BASIC RESEARCH USING ANIMAL MODELS
MODERN BIOBUBBLE UNITS TO SUPPORT BASIC RESEARCH USING ANIMAL MODELS
批准号:
421965-2012
负责人:
Ma, David
金额:
$8.69万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
我们的研究小组进行生理学和新陈代谢方面的基础研究。动物模型是基础科学研究的重要工具。特别是,越来越多的转基因小鼠或独特繁殖的大鼠模型已经变得唾手可得。没有这些模型,我们对生理学和新陈代谢的基本理解就不可能取得许多重大进展。我们的部门经历了巨大的增长通过雇用7名新教师和现有研究项目的增长。在满足当前需要和继续扩大研究活动方面存在着重大障碍。我们需要一个生物气泡装置来满足我们的迫切需求,以解决一个关键的需求,不仅支持现有的和新的教职员工的需求,而且还推进新领域的研究。这些单位允许用于癌症、免疫学和肠道研究的专门研究动物(小鼠、大鼠和兔子模型)的住房,需要高水平的环境控制。目前,我们的工厂已经达到了最大产能。通过使用尖端的生物泡装置,可以很容易地实现膨胀。这些单元也具有很高的成本效益,其成本是传统和昂贵的砖和砂浆房间的三分之一,这些房间需要与建筑基础设施相连接的专门的湿度和空气交换系统。拟议的生物气泡装置的收购将满足15个研究实验室和100多名受训人员的巨大需求。
英文摘要
Our team of investigators conduct basic research in physiology and metabolism. Animal models are important tools in basic science research. In particular, there are growing numbers of genetically altered mice or uniquely bred rat models that have become readily available. Without these models many significant advances in our fundamental understanding of physiology and metabolism would not be possible. Our department has experienced tremendous growth through the hiring of 7 new faculty hires and also growth of existing research programs. A significant barrier exists to meeting current needs and continued expansion of research activities. We are in need of a biobubble units to meet our urgent needs to address a critical need to not only support the needs of existing and new faculty hires, but also to advance research into new areas. These units permit the housing of specialized research animals (mouse, rat and rabbit models) used in cancer, immunology and gut research, requiring a high level of environmental containment. Currently, we are at maximum capacity in our facility. Expansion can be readily achieved through the use of cutting edge biobubble units. These units are also highly cost effective and at a third of the cost of traditional and expensive brick and mortar rooms that require specialized humidity and air exchange systems linked to the building infrastructure. The acquisition of a the proposed biobubble units will address a significant need for 15 researcher laboratories and upwards of 100 of their trainees.
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依托单位:
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Mechanisms underlying the biological function of fatty acids
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依托单位:
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依托单位:
Structure, function and mechanisms by which fatty acids modulate cellular signalling
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依托单位:
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批准号:430299-2012
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财政年份:2012
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依托单位:
Structure, function and mechanisms by which fatty acids modulate cellular signalling
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项目类别:Discovery Grants Program - Individual
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依托单位:
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项目类别:University Undergraduate Student Research Awards
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依托单位:
Structure, function and mechanisms by which fatty acids modulate cellular signalling
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财政年份:2011
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依托单位:
Food for Health Workshop
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批准号:415573-2011
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财政年份:2011
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依托单位:
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Modern cage washer to support basic research using rodent models
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Cellular and molecular mechanisms by which dietary fatty acids inhibit cancer
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财政年份:2009
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依托单位:
Cellular and molecular mechanisms by which dietary fatty acids inhibit cancer
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项目类别:Discovery Grants Program - Individual
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依托单位:
Cellular and molecular mechanisms by which dietary fatty acids inhibit cancer
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Gas chromatography system for basic research on the role of lipids on human health and disease
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批准号:360321-2008
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