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Solution- and Solid-State 500 MHz Nuclear Magnetic Resonance Facility Upgrade

溶液和固态 500 MHz 核磁共振设施升级

基本信息

批准号：
423194-2012
负责人：
Hazendonk, Paul
金额：
$ 10.93万
依托单位：
University of Lethbridge
依托单位国家：
加拿大
项目类别：
Research Tools and Instruments - Category 1 (<$150,000)
财政年份：
2011
资助国家：
加拿大
起止时间：
2011-01-01 至 2012-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=495900
关键词：
Solution Solid State 500 MHz

项目摘要

The applicants request support for upgrading the University of Lethbridge's 500 MHz nuclear magnetic resonance (NMR) spectrometer. NMR spectroscopy is the main tool used to analyze molecular structures and dynamics of pure compounds, mixtures and biological samples. This instrument has been the mainstay of the NMR facility over the last ten years. It serves 24 principle investigators at or in collaboration with those at the University of Lethbridge in research areas including: materials science, inorganic chemistry, organic chemistry, catalysis, biophysics, environmental science, energy research, and NMR imaging. The NMR facility is central to the training of numerous undergraduate and graduate students and postdoctoral fellows. Our facility is especially optimized for the study of fluorine-containing materials. Fluorine is present in 40% of all pharmaceuticals, and is used extensively in materials related to alternative energy, environmental technology, and electronics applications. The study of this element, however, places special demands on NMR instrumentation and experiments. A refurbished 500 MHz NMR spectrometer is the essential component of the centre of excellence at the University of Lethbridge in applied fluorine chemistry, which is unique in the world. The proposed series of modifications will have the maximum impact in the most cost effective manner, thereby enabling continuation of scientific excellence and training of the next generation of scientists. This investment represents a mere 12.5% of the estimated cost of full replacement and will extend the operational lifetime of the instrument by at least 10 years. This upgrade will allow the University of Lethbridge to continue to define the cutting edge of modern fluorine chemistry.

申请者要求支持莱斯布里奇大学的500兆赫核磁共振（NMR）光谱仪的升级。核磁共振波谱是用于分析纯化合物、混合物和生物样品的分子结构和动力学的主要工具。在过去的十年中，该仪器一直是核磁共振设备的支柱。研究领域包括材料科学、无机化学、有机化学、催化、生物物理学、环境科学、能源研究和核磁共振成像，为莱斯布里奇大学的24名主要研究人员提供服务或与他们合作。核磁共振设施是培训众多本科生、研究生和博士后的中心。我们的设备特别适合含氟材料的研究。氟存在于40%的药品中，并广泛用于与替代能源、环境技术和电子应用相关的材料中。然而，这种元素的研究对核磁共振仪器和实验提出了特殊的要求。翻新的500 MHz核磁共振光谱仪是莱斯布里奇大学应用氟化学卓越中心的重要组成部分，这在世界上是独一无二的。拟议的一系列修改将以最具成本效益的方式产生最大的影响，从而能够继续保持科学卓越和培养下一代科学家。这项投资仅占全面更换估计成本的12.5%，并将延长仪器的使用寿命至少10年。这次升级将使莱斯布里奇大学继续定义现代氟化学的前沿。