Evaluating the Role of Clozapine modulation of the GABAergic neurotransmission in Schizophrenia

评估氯氮平对精神分裂症 GABA 能神经传递的调节作用

• 批准号: 174346
• 负责人: Daskalakis Zafiris J
• 金额: --
• 依托单位: Centre for Addiction and Mental Health (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2009-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=174346&lang=en
• 关键词: Animal Models; Gaba; Neurophysiology; Pharmacology; Receptor; Schizophrenia

Dysfunctional brain inhibition has been suggested as a mechanism through which symptoms of schizophrenia occur. Brain inhibition refers to a process in which inhibitory neurons reduce excessive brain activity. Excessive brain activity, in turn, has been

大脑抑制功能障碍被认为是精神分裂症症状发生的一种机制。大脑抑制是指抑制神经元减少过度的大脑活动的过程。反过来，过度的大脑活动也是