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Optimizing hypothermic neuroprotection to recover fine synaptic structure and sensorimotor function in vivo following cerebral ischemia and reperfusion

Optimizing hypothermic neuroprotection to recover fine synaptic structure and sensorimotor function in vivo following cerebral ischemia and reperfusion
优化低温神经保护以恢复脑缺血再灌注后体内精细突触结构和感觉运动功能
批准号：
247890
负责人：
Xie Yicheng
金额：
$10.93万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-11-01 至 2014-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=247890&lang=en
关键词：
Channelrhodopsin-2 Dendritic Spine Excitability Hypothermia Intrinsic Optical Signal Imaging Stroke Structural Plasticity Two Photon Imaging Voltage Sensor Dye Imaging

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中文摘要
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英文摘要
The only widely validated treatment for both global and focal stroke that does not involve induction of reperfusion is hypothermia. However, there is a risk of central nervous system side effects (e.g., impaired plasticity). Moreover, the mechanism of neu
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In vitro and in vivo functional assessment of neuropsychiatric disease-related synaptic gene mutations
  • 批准号：
    338604
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $9.83万
  • 财政年份：
    2015
  • 负责人：
    Xie Yicheng
  • 依托单位：
    University of British Columbia
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