Direct conversion of human skin fibroblasts to the lymphoid lineages

人皮肤成纤维细胞直接转化为淋巴谱系

• 批准号: 247477
• 负责人: Kushwah Rahul
• 金额: $ 10.2万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-11-01 至 2013-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=247477&lang=en
• 关键词: B Cells; Direct Conversion; Fibroblasts; Lymphopoiesis; T Cells

T and B cells are major constituents of white blood cells and play a key role in fighting infections. However in diseases such as HIV and leukemia, there is a lack of functional T and B cells and these diseases lack robust treatments and require constant

T和B细胞是白色血细胞的主要成分，在抵抗感染中起着关键作用。然而，在诸如HIV和白血病的疾病中，缺乏功能性T和B细胞，并且这些疾病缺乏稳健的治疗并且需要持续的免疫治疗。