Abnormal vascular morphology and function in mice homozygous for hypomorphic allele of the c-myb proto-oncogene

c-myb原癌基因亚等位基因纯合子小鼠血管形态和功能异常

• 批准号: 253737
• 负责人: Shikatani Eric A
• 金额: $ 0.06万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2012-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253737&lang=en
• 关键词: Atherosclerosis; Cardiovascular Disease; Cell Biology; Hypertension; Mouse Models Of Disease; Restenosis; Vascular Smooth Muscle

Our lab has previously shown that the gene c-myb is involved in the growth of vascular smooth muscle cells (VSMCs). These VSMCs are important to research as diseases such as hypertension, atherosclerosis and restenosis of stented arteries all involve the

我们的实验室先前已经表明，基因c-myb参与血管平滑肌细胞（VSMC）的生长。 这些血管平滑肌细胞对于研究是重要的，因为诸如高血压、动脉粥样硬化和支架动脉再狭窄的疾病都涉及血管平滑肌细胞。