Pattern-discovery and related algorithms
模式发现和相关算法
基本信息
- 批准号:8042-2009
- 负责人:
- 金额:$ 1.38万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2012
- 资助国家:加拿大
- 起止时间:2012-01-01 至 2013-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Identifying significant relationships in an uncertain environment, using data from multiple sources, is extremely important in discovering novelty in pattern discovery. For example, linking genotype and phenotype attributes plays a vital role in understanding the biological processes, under normal or novel conditions involving genetic modifications and changes, in problems such as the engineering of novel bioproducts. We propose to study biological processes as an information system that includes identifying relationships of functional segments and molecular sites of biomolecules, and aim at understanding their effects on biomolecular structure and functionality. We study the problem as a data-mining problem using the paradigm of granular computing and propose analysis methods based on different types of multiple-value (multi-attribute) association patterns extracted from an alignment of data. The patterns are based on analysis of statistical testing from a prior model. The goal is to provide a very flexible analysis/synthesis through selection, partitioning and attribute clustering etc. of the data. The paradigm incorporating hierarchical and modular analysis aims at a more generalized model than contiguous sequential pattern analysis and is more descriptive than multiple-variable analysis. After detecting significant patterns, further pattern-mining methods to understand the inter-pattern relationships will be developed.
在不确定的环境中,使用来自多个来源的数据来识别重要的关系,对于在模式发现中发现新奇是非常重要的。例如,将基因型和表型属性联系起来,在理解生物学过程中起着至关重要的作用,在正常或新的条件下,涉及遗传修饰和变化,在诸如新生物产品工程的问题中。我们建议将生物过程作为一个信息系统来研究,包括识别生物分子的功能片段和分子位点之间的关系,并旨在了解它们对生物分子结构和功能的影响。我们研究的问题作为一个数据挖掘问题,使用粒度计算的范式,并提出分析方法的基础上不同类型的多值(多属性)关联模式提取的对齐数据。这些模式是基于对先前模型的统计测试的分析。目标是通过数据的选择、划分和属性聚类等提供非常灵活的分析/综合。结合层次和模块化分析的范式旨在建立一个比连续序列模式分析更一般化的模型,并且比多变量分析更具描述性。在检测到重要模式后,将开发进一步的模式挖掘方法来理解模式间的关系。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Chiu, David其他文献
Just-in-time vaccines: Biomineralized calcium phosphate core-immunogen shell nanoparticles induce long-lasting CD8(+) T cell responses in mice.
- DOI:
10.1016/j.nano.2013.11.007 - 发表时间:
2014-04 - 期刊:
- 影响因子:5.4
- 作者:
Zhou, Weibin;Moguche, Albanus O.;Chiu, David;Murali-Krishna, Kaja;Baneyx, Francois - 通讯作者:
Baneyx, Francois
Psychological Distress Independently Predicts Prolonged Hospitalization After Primary Total Hip and Knee Arthroplasty
- DOI:
10.1016/j.arth.2019.03.063 - 发表时间:
2019-08-01 - 期刊:
- 影响因子:3.5
- 作者:
Halawi, Mohamad J.;Chiu, David;Cote, Mark P. - 通讯作者:
Cote, Mark P.
Enrollment volume effect on risk factor control and outcomes in the SAMMPRIS trial
- DOI:
10.1212/wnl.0000000000002191 - 发表时间:
2015-12-15 - 期刊:
- 影响因子:9.9
- 作者:
Chiu, David;Klucznik, Richard P.;Chimowitz, Marc I. - 通讯作者:
Chimowitz, Marc I.
Structural characterization of a monomethylauristatin-E based ADC that contains 8 drugs conjugated at interchain cysteine residues
- DOI:
10.1016/j.jpba.2021.114309 - 发表时间:
2021-08-14 - 期刊:
- 影响因子:3.4
- 作者:
Chiu, David;Pan, Lucy;Valliere-Douglass, John - 通讯作者:
Valliere-Douglass, John
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
- DOI:
10.1016/s0140-6736(13)62038-3 - 发表时间:
2014-01-25 - 期刊:
- 影响因子:168.9
- 作者:
Derdeyn, Colin P.;Chimowitz, Marc I.;Lynn, Michael J.;Fiorella, David;Turan, Tanya N.;Janis, L. Scott;Montgomery, Jean;Nizam, Azhar;Lane, Bethany F.;Lutsep, Helmi L.;Barnwell, Stanley L.;Waters, Michael F.;Hoh, Brian L.;Hourihane, J. Maurice;Levy, Elad I.;Alexandrov, Andrei V.;Harrigan, Mark R.;Chiu, David;Klucznik, Richard P.;Clark, Joni M.;McDougall, Cameron G.;Johnson, Mark D.;Pride, G. Lee, Jr.;Lynch, John R.;Zaidat, Osama O.;Rumboldt, Zoran;Cloft, Harry J. - 通讯作者:
Cloft, Harry J.
Chiu, David的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Chiu, David', 18)}}的其他基金
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2013
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2011
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2010
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2009
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Experimental explorations from systemic informatics of biosquences
生物序列系统信息学的实验探索
- 批准号:
8042-2004 - 财政年份:2008
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Experimental explorations from systemic informatics of biosquences
生物序列系统信息学的实验探索
- 批准号:
8042-2004 - 财政年份:2007
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Experimental explorations from systemic informatics of biosquences
生物序列系统信息学的实验探索
- 批准号:
8042-2004 - 财政年份:2006
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Experimental explorations from systemic informatics of biosquences
生物序列系统信息学的实验探索
- 批准号:
8042-2004 - 财政年份:2005
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Experimental explorations from systemic informatics of biosquences
生物序列系统信息学的实验探索
- 批准号:
8042-2004 - 财政年份:2004
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Understanding the algorithmic discovery process: an empirical approach
了解算法发现过程:实证方法
- 批准号:
8042-2000 - 财政年份:2003
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
相似海外基金
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2013
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2011
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2010
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
Pattern-discovery and related algorithms
模式发现和相关算法
- 批准号:
8042-2009 - 财政年份:2009
- 资助金额:
$ 1.38万 - 项目类别:
Discovery Grants Program - Individual
A Platform for Pattern-Based Proteomic Biomarker Discovery-R01
基于模式的蛋白质组生物标志物发现平台-R01
- 批准号:
7929393 - 财政年份:2009
- 资助金额:
$ 1.38万 - 项目类别:
A Platform for Pattern-Based Proteomic Biomarker Discovery-R01
基于模式的蛋白质组生物标志物发现平台-R01
- 批准号:
7878479 - 财政年份:2006
- 资助金额:
$ 1.38万 - 项目类别:
A Platform for Pattern-Based Proteomic Biomarker Discovery-R01
基于模式的蛋白质组生物标志物发现平台-R01
- 批准号:
7484093 - 财政年份:2006
- 资助金额:
$ 1.38万 - 项目类别:
A Platform for Pattern-Based Proteomic Biomarker Discovery-R01
基于模式的蛋白质组生物标志物发现平台-R01
- 批准号:
7293576 - 财政年份:2006
- 资助金额:
$ 1.38万 - 项目类别:
Interaction Pattern Based Predictor of Protein Structure
基于相互作用模式的蛋白质结构预测器
- 批准号:
8214586 - 财政年份:1994
- 资助金额:
$ 1.38万 - 项目类别:
Interaction Pattern Based Predictor of Protein Structure
基于相互作用模式的蛋白质结构预测器
- 批准号:
7776838 - 财政年份:1994
- 资助金额:
$ 1.38万 - 项目类别: