Exploring stochasticity in the spatio-temporal patterns of coordinated brain activity

探索协调大脑活动的时空模式的随机性

• 批准号: 227059-2012
• 负责人: PerezVelazquez, JoseLuis
• 金额: $ 2.26万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=506643
• 关键词: Exploring; stochasticity; spatio; temporal; patterns

The development of new methods and theoretical frameworks to understand brain function at behaviourally relevant time scales is one of the most challenging frontiers in neuroscience research. The complexity of these problems needs a multidisciplinary approach. We have established a line of research to study patterns of brain activity, in terms of synchronization of the cellular activities within brain networks, and how these patterns relate to specific cognitive functions and to brain pathologies. Our line of research is based on the notion that brain function results from the transient coordinated activity of neuronal networks in diverse brain regions. Our long-term goal is to understand the functional role of brain rhythms in information processing, and our short-term goals aim at the investigation of the variability and complexity of the brain patterns that we record with various methods in humans and animals.

开发新方法和理论框架来了解行为相关时间尺度的大脑功能是神经科学研究中最具挑战性的前沿之一。这些问题的复杂性需要采取多学科的方法。我们已经建立了一系列研究来研究大脑活动模式，包括大脑网络内细胞活动的同步性，以及这些模式与特定认知功能和大脑病理学的关系。我们的研究方向基于这样的概念：大脑功能是由不同大脑区域的神经元网络的瞬时协调活动产生的。我们的长期目标是了解大脑节律在信息处理中的功能作用，我们的短期目标旨在研究我们用各种方法记录的人类和动物大脑模式的变异性和复杂性。